Ubiquinol (reduced Coenzyme Q10) in patients with severe sepsis or septic shock: a randomized, double-blind, placebo-controlled, pilot trial

INTRODUCTION: We previously found decreased levels of Coenzyme Q10 (CoQ10) in patients with septic shock. The objective of the current study was to assess whether the provision of exogenous ubiquinol (the reduced form of CoQ10) could increase plasma CoQ10 levels and improve mitochondrial function. M...

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Detalhes bibliográficos
Publicado no:Crit Care
Main Authors: Donnino, Michael W., Mortensen, Sharri J., Andersen, Lars W., Chase, Maureen, Berg, Katherine M., Balkema, Julia, Radhakrishnan, Jeejabai, Gazmuri, Raúl J., Liu, Xiaowen, Cocchi, Michael N.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520066/
https://ncbi.nlm.nih.gov/pubmed/26130237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-015-0989-3
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