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Ubiquinol (reduced Coenzyme Q10) in patients with severe sepsis or septic shock: a randomized, double-blind, placebo-controlled, pilot trial

INTRODUCTION: We previously found decreased levels of Coenzyme Q10 (CoQ10) in patients with septic shock. The objective of the current study was to assess whether the provision of exogenous ubiquinol (the reduced form of CoQ10) could increase plasma CoQ10 levels and improve mitochondrial function. M...

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Bibliographische Detailangaben
Veröffentlicht in:Crit Care
Hauptverfasser: Donnino, Michael W., Mortensen, Sharri J., Andersen, Lars W., Chase, Maureen, Berg, Katherine M., Balkema, Julia, Radhakrishnan, Jeejabai, Gazmuri, Raúl J., Liu, Xiaowen, Cocchi, Michael N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520066/
https://ncbi.nlm.nih.gov/pubmed/26130237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-015-0989-3
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