Ubiquinol (reduced Coenzyme Q10) in patients with severe sepsis or septic shock: a randomized, double-blind, placebo-controlled, pilot trial

INTRODUCTION: We previously found decreased levels of Coenzyme Q10 (CoQ10) in patients with septic shock. The objective of the current study was to assess whether the provision of exogenous ubiquinol (the reduced form of CoQ10) could increase plasma CoQ10 levels and improve mitochondrial function. M...

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Publicat a:Crit Care
Autors principals: Donnino, Michael W., Mortensen, Sharri J., Andersen, Lars W., Chase, Maureen, Berg, Katherine M., Balkema, Julia, Radhakrishnan, Jeejabai, Gazmuri, Raúl J., Liu, Xiaowen, Cocchi, Michael N.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520066/
https://ncbi.nlm.nih.gov/pubmed/26130237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-015-0989-3
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