Pyruvate Dehydrogenase Activity Is Decreased in the Peripheral Blood Mononuclear Cells of Patients with Sepsis. A Prospective Observational Trial

Rationale: Rodent studies have shown that pyruvate dehydrogenase (PDH) levels are low in sepsis. This may cause cells to shift to anaerobic metabolism, resulting in increased lactate production. Alterations in PDH during sepsis have never been studied in humans. Objectives: The objective of this pil...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Ann Am Thorac Soc
Prif Awduron: Nuzzo, Erin, Berg, Katherine M., Andersen, Lars W., Balkema, Julia, Montissol, Sophia, Cocchi, Michael N., Liu, Xiaowen, Donnino, Michael W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2015
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724894/
https://ncbi.nlm.nih.gov/pubmed/26356483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201505-267BC
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