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Sarcoplasmic Reticulum Structure and Functional Properties that Promote Long-Lasting Calcium Sparks
Calcium (Ca) sparks are the fundamental sarcoplasmic reticulum (SR) Ca release events in cardiac myocytes, and they have a typical duration of 20–40 ms. However, when a fraction of ryanodine receptors (RyRs) are blocked by tetracaine or ruthenium red, Ca sparks lasting hundreds of milliseconds have...
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| Veröffentlicht in: | Biophys J |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4724649/ https://ncbi.nlm.nih.gov/pubmed/26789761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.12.009 |
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