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Increasing SERCA function promotes initiation of calcium sparks and breakup of calcium waves
Waves of sarcoplasmic reticulum (SR) calcium (Ca) release can cause arrhythmogenic afterdepolarizations in cardiac myocytes. Ca waves propagate when Ca sparks at one Ca release unit (CRUs) recruit new Ca sparks at neighboring CRUs. Under normal conditions, Ca sparks are too small to recruit neighbor...
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| Udgivet i: | J Physiol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8249358/ https://ncbi.nlm.nih.gov/pubmed/33963531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP281579 |
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