Lataa...
Targeted mutagenesis of DNA using triple helix-forming oligonucleotides linked to psoralen.
Oligonucleotides can bind as third strands of DNA in a sequence-specific manner in the major groove in homopurine/homopyrimidine stretches in duplex DNA. Here we use a 10-base triplex-forming oligonucleotide linked to a psoralen derivative at its 5' end to achieve site-specific, targeted mutage...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
1993
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC47246/ https://ncbi.nlm.nih.gov/pubmed/8356097 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|