A potential role of X-linked inhibitor of apoptosis protein in mitochondrial membrane permeabilization and its implication in cancer therapy

X-chromosome-linked inhibitor of apoptosis protein (XIAP) has an important regulatory role in programmed cell death by inhibiting the caspase cascade. Activation of XIAP-dependent signaling culminates into regulation of multiple cellular processes including apoptosis, innate immunity, epithelial-to-...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Drug Discov Today
Hlavní autoři: Chaudhary, Ajay K., Yadav, Neelu, Bhat, Tariq A., O'Malley, Jordan, Kumar, Sandeep, Chandra, Dhyan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724570/
https://ncbi.nlm.nih.gov/pubmed/26232549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2015.07.014
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky