Nimbolide reduces CD44 positive cell population and induces mitochondrial apoptosis in pancreatic cancer cells

Pancreatic ductal adenocarcinoma (PDAC) is highly aggressive disease and current treatment regimens fail to effectively cure PDAC. Development of resistance to current therapy is one of the key reasons for this outcome. Nimbolide (NL), a triterpenoid obtained from Azadirachta indica, exhibits antica...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cancer Lett
Hauptverfasser: Kumar, Sandeep, Inigo, Joseph R., Kumar, Rahul, Chaudhary, Ajay K., O’Malley, Jordan, Balachandar, Srimmitha, Wang, Jianmin, Attwood, Kristopher, Yadav, Neelu, Hochwald, Steven, Wang, Xinjiang, Chandra, Dhyan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706561/
https://ncbi.nlm.nih.gov/pubmed/29107110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.10.029
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge