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Restoration of mitochondria function as a target for cancer therapy
Defective oxidative phosphorylation has a crucial role in the attenuation of mitochondrial function, which confers therapy resistance in cancer. Various factors, including endogenous heat shock proteins (HSPs) and exogenous agents such as dichloroacetate, restore respiratory and other physiological...
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| Publicado no: | Drug Discov Today |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4433775/ https://ncbi.nlm.nih.gov/pubmed/25766095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2015.03.001 |
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