Mitochondrial dysfunction-mediated apoptosis resistance associates with defective heat shock protein response in African–American men with prostate cancer

BACKGROUND: African–American (AA) patients with prostate cancer (PCa) respond poorly to current therapy compared with Caucasian American (CA) PCa patients. Although underlying mechanisms are not defined, mitochondrial dysfunction is a key reason for this disparity. METHODS: Cell death, cell cycle, a...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Chaudhary, Ajay K, Bhat, Tariq A, Kumar, Sandeep, Kumar, Anil, Kumar, Rahul, Underwood, Willie, Koochekpour, Shahriar, Shourideh, Mojgan, Yadav, Neelu, Dhar, Shanta, Chandra, Dhyan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865976/
https://ncbi.nlm.nih.gov/pubmed/27115471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.88
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