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Osteoprotegerin inhibits bone resorption and prevents tumor development in a xenogenic model of Ewing's sarcoma by inhibiting RANKL

Ewing's sarcoma (ES) associated with high osyeolytic lesions typically arises in the bones of children and adolescents. The development of multi-disciplinary therapy has increased current long-term survival rates to greater than 50% but only 20% for high risk group patients (relapse, metastases...

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Bibliographic Details
Published in:J Bone Oncol
Main Authors: Picarda, Gaëlle, Matous, Etienne, Amiaud, Jérôme, Charrier, Céline, Lamoureux, François, Heymann, Marie-Françoise, Tirode, Franck, Pitard, Bruno, Trichet, Valérie, Heymann, Dominique, Redini, Françoise
Format: Artigo
Language:Inglês
Published: Elsevier 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4723385/
https://ncbi.nlm.nih.gov/pubmed/26909278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbo.2013.04.004
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