Zoledronic acid inhibits pulmonary metastasis dissemination in a preclinical model of Ewing’s sarcoma via inhibition of cell migration

BACKGROUND: Ewing’s sarcoma (ES) is the second most frequent primitive malignant bone tumor in adolescents with a very poor prognosis for high risk patients, mainly when lung metastases are detected (overall survival <15% at 5 years). Zoledronic acid (ZA) is a potent inhibitor of bone resorption...

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Hauptverfasser: Odri, Guillaume, Kim, Pui-Pui, Lamoureux, François, Charrier, Céline, Battaglia, Séverine, Amiaud, Jérôme, Heymann, Dominique, Gouin, François, Redini, Françoise
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975287/
https://ncbi.nlm.nih.gov/pubmed/24612486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-169
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