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TRAIL receptor signaling and therapeutic option in bone tumors: the trap of the bone microenvironment

Tumor Necrosis Factor-Related Apoptosis Inducing Ligand (TRAIL/TNFSF10) has been reported to specifically induce malignant cell death being relatively nontoxic to normal cells. Since its identification 15 years ago, the antitumor activity and therapeutic value of TRAIL have been extensively studied....

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Detalhes bibliográficos
Main Authors: Picarda, Gaëlle, Trichet, Valérie, Téletchéa, Stéphane, Heymann, Dominique, Rédini, Françoise
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236571/
https://ncbi.nlm.nih.gov/pubmed/22206045
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