New Insights about the Wnt/β-Catenin Signaling Pathway in Primary Bone Tumors and Their Microenvironment: A Promising Target to Develop Therapeutic Strategies?

Osteosarcoma and Ewing sarcoma are the most common malignant primary bone tumors mainly occurring in children, adolescents and young adults. Current standard therapy includes multidrug chemotherapy and/or radiation specifically for Ewing sarcoma, associated with tumor resection. However, patient sur...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Danieau, Geoffroy, Morice, Sarah, Rédini, Françoise, Verrecchia, Franck, Brounais-Le Royer, Bénédicte
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6696068/
https://ncbi.nlm.nih.gov/pubmed/31370265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20153751
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