TRAIL receptor signaling and therapeutic option in bone tumors: the trap of the bone microenvironment

Tumor Necrosis Factor-Related Apoptosis Inducing Ligand (TRAIL/TNFSF10) has been reported to specifically induce malignant cell death being relatively nontoxic to normal cells. Since its identification 15 years ago, the antitumor activity and therapeutic value of TRAIL have been extensively studied....

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Bibliographic Details
Main Authors: Picarda, Gaëlle, Trichet, Valérie, Téletchéa, Stéphane, Heymann, Dominique, Rédini, Françoise
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2011
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236571/
https://ncbi.nlm.nih.gov/pubmed/22206045
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