Improved Muscle Function in Duchenne Muscular Dystrophy through L-Arginine and Metformin: An Investigator-Initiated, Open-Label, Single-Center, Proof-Of-Concept-Study

Altered neuronal nitric oxide synthase function in Duchenne muscular dystrophy leads to impaired mitochondrial function which is thought to be one cause of muscle damage in this disease. The study tested if increased intramuscular nitric oxide concentration can improve mitochondrial energy metabolis...

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書誌詳細
出版年:PLoS One
主要な著者: Hafner, Patricia, Bonati, Ulrike, Erne, Beat, Schmid, Maurice, Rubino, Daniela, Pohlman, Urs, Peters, Thomas, Rutz, Erich, Frank, Stephan, Neuhaus, Cornelia, Deuster, Stefanie, Gloor, Monika, Bieri, Oliver, Fischmann, Arne, Sinnreich, Michael, Gueven, Nuri, Fischer, Dirk
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2016
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4723144/
https://ncbi.nlm.nih.gov/pubmed/26799743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147634
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