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PDGF-DEPENDENT β-CATENIN ACTIVATION IS ASSOCIATED WITH ABNORMAL PULMONARY ARTERY SMOOTH MUSCLE CELL PROLIFERATION IN PULMONARY ARTERIAL HYPERTENSION
Pulmonary arterial hypertension (PAH) is characterized by excessive pulmonary arterial smooth muscle cells (PASMCs) growth, partially in response to PDGF-BB but whether this is dependent on β-catenin (βC) activation is unclear. Compared to healthy cells, PAH PASMCs demonstrate higher levels of proli...
Gardado en:
| Publicado en: | FEBS Lett |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4722963/ https://ncbi.nlm.nih.gov/pubmed/26787464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12038 |
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