Smooth Muscle Proliferation and Role of the Prostacyclin (IP) Receptor in Idiopathic Pulmonary Arterial Hypertension

Rationale: Prostacyclin analogs, used to treat idiopathic pulmonary arterial hypertension (IPAH), are assumed to work through prostacyclin (IP) receptors linked to cyclic AMP (cAMP) generation, although the potential to signal through peroxisome proliferator-activated receptor-γ (PPARγ) exists. Obje...

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Detalhes bibliográficos
Main Authors: Falcetti, Emilia, Hall, Susan M., Phillips, Peter G., Patel, Jigisha, Morrell, Nicholas W., Haworth, Sheila G., Clapp, Lucie H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
Assuntos:
E. Pulmonary Vascular Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001258/
https://ncbi.nlm.nih.gov/pubmed/20622039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201001-0011OC
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