Serine/threonine phosphorylation regulates binding of C hnRNP proteins to pre-mRNA.
The C hnRNP proteins bind to nascent pre-mRNA and are thought to participate in an early step of the pre-mRNA splicing pathway. We report here that C hnRNP proteins are phosphorylated by a casein kinase II activity in a HeLa cell nuclear extract and that dephosphorylation of C hnRNP proteins is inhi...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
|---|---|
| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1993
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47223/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8356082/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.16.7764 |
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