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Serine/threonine phosphorylation regulates binding of C hnRNP proteins to pre-mRNA.

The C hnRNP proteins bind to nascent pre-mRNA and are thought to participate in an early step of the pre-mRNA splicing pathway. We report here that C hnRNP proteins are phosphorylated by a casein kinase II activity in a HeLa cell nuclear extract and that dephosphorylation of C hnRNP proteins is inhi...

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Bibliographic Details
Main Authors: Mayrand, S H, Dwen, P, Pederson, T
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC47223/
https://ncbi.nlm.nih.gov/pubmed/8356082
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