Anti-CD45 radioimmunotherapy without TBI before transplantation facilitates persistent haploidentical donor engraftment

Many patients with hematologic malignancies cannot tolerate hematopoietic cell transplantation (HCT), whereas others may not have a compatible human leukocyte antigen–matched donor. To overcome these limitations, we optimized a conditioning regimen employing anti-CD45 radioimmunotherapy (RIT) replac...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Orozco, Johnnie J., Kenoyer, Aimee, Balkin, Ethan R., Gooley, Ted A., Hamlin, Donald K., Wilbur, D. Scott, Hylarides, Mark D., Frost, Sofia H. L., Mawad, Raya, O’Donnell, Paul, Sandmaier, Brenda M., Fuchs, Ephraim J., Luznik, Leo, Green, Damian J., Gopal, Ajay K., Press, Oliver W., Pagel, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722286/
https://ncbi.nlm.nih.gov/pubmed/26576864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-12-617019
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