Comparative analysis of bispecific antibody and streptavidin-targeted radioimmunotherapy for B cell cancers

Streptavidin (SA)-biotin pretargeted radioimmunotherapy (PRIT) that targets CD20 in non-Hodgkin lymphoma (NHL) exhibits remarkable efficacy in model systems, but SA immunogenicity and interference by endogenous biotin may complicate clinical translation of this approach. In this study, we engineered...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Green, Damian J., Frayo, Shani L., Lin, Yukang, Hamlin, Donald K., Fisher, Darrell R., Frost, Sofia H.L., Kenoyer, Aimee L., Hylarides, Mark D., Gopal, Ajay K., Gooley, Theodore A., Orozco, Johnnie J., Till, Brian G., O’Steen, Shyril, Orcutt, Kelly D., Wilbur, D. Scott, Wittrup, K. Dane, Press, Oliver W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290195/
https://ncbi.nlm.nih.gov/pubmed/27590740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-0571
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