Anti-CD45 Radioimmunotherapy with (90)Y but Not (177)Lu Is Effective Treatment in a Syngeneic Murine Leukemia Model

Radioimmunotherapy (RIT) for treatment of hematologic malignancies has primarily employed monoclonal antibodies (Ab) labeled with (131)I or (90)Y which have limitations, and alternative radionuclides are needed to facilitate wider adoption of RIT. We therefore compared the relative therapeutic effic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Orozco, Johnnie J., Balkin, Ethan R., Gooley, Ted A., Kenoyer, Aimee, Hamlin, Donald K., Wilbur, D. Scott, Fisher, Darrell R., Hylarides, Mark D., Shadman, Mazyar, Green, Damian J., Gopal, Ajay K., Press, Oliver W., Pagel, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252056/
https://ncbi.nlm.nih.gov/pubmed/25460570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113601
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