Comparative Efficacy of (177)Lu and (90)Y for Anti-CD20 Pretargeted Radioimmunotherapy in Murine Lymphoma Xenograft Models

PURPOSE: Pretargeted radioimmunotherapy (PRIT) is a multi-step method of selectively delivering high doses of radiotherapy to tumor cells while minimizing exposure to surrounding tissues. Yttrium-90 ((90)Y) and lutetium-177 ((177)Lu) are two of the most promising beta-particle emitting radionuclides...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Frost, Sofia H. L., Frayo, Shani L., Miller, Brian W., Orozco, Johnnie J., Booth, Garrett C., Hylarides, Mark D., Lin, Yukang, Green, Damian J., Gopal, Ajay K., Pagel, John M., Bäck, Tom A., Fisher, Darrell R., Press, Oliver W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364776/
https://ncbi.nlm.nih.gov/pubmed/25785845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120561
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