Comparative Efficacy of (177)Lu and (90)Y for Anti-CD20 Pretargeted Radioimmunotherapy in Murine Lymphoma Xenograft Models

PURPOSE: Pretargeted radioimmunotherapy (PRIT) is a multi-step method of selectively delivering high doses of radiotherapy to tumor cells while minimizing exposure to surrounding tissues. Yttrium-90 ((90)Y) and lutetium-177 ((177)Lu) are two of the most promising beta-particle emitting radionuclides...

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發表在:PLoS One
Main Authors: Frost, Sofia H. L., Frayo, Shani L., Miller, Brian W., Orozco, Johnnie J., Booth, Garrett C., Hylarides, Mark D., Lin, Yukang, Green, Damian J., Gopal, Ajay K., Pagel, John M., Bäck, Tom A., Fisher, Darrell R., Press, Oliver W.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364776/
https://ncbi.nlm.nih.gov/pubmed/25785845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120561
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