Comparative Efficacy of (177)Lu and (90)Y for Anti-CD20 Pretargeted Radioimmunotherapy in Murine Lymphoma Xenograft Models

PURPOSE: Pretargeted radioimmunotherapy (PRIT) is a multi-step method of selectively delivering high doses of radiotherapy to tumor cells while minimizing exposure to surrounding tissues. Yttrium-90 ((90)Y) and lutetium-177 ((177)Lu) are two of the most promising beta-particle emitting radionuclides...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Frost, Sofia H. L., Frayo, Shani L., Miller, Brian W., Orozco, Johnnie J., Booth, Garrett C., Hylarides, Mark D., Lin, Yukang, Green, Damian J., Gopal, Ajay K., Pagel, John M., Bäck, Tom A., Fisher, Darrell R., Press, Oliver W.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364776/
https://ncbi.nlm.nih.gov/pubmed/25785845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120561
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