Pseudomonas aeruginosa Bacteremic Patients Exhibit Nonprotective Antibody Titers Against Therapeutic Antibody Targets PcrV and Psl Exopolysaccharide

Background. The type 3 secretion protein PcrV and Psl exopolysaccharide are promising therapeutic antibody targets against Pseudomonas aeruginosa. We examined P. aeruginosa bloodstream infection (BSI) isolates for the ability to express PcrV and Psl and evaluated corresponding patient serum for acti...

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Bibliografiske detaljer
Udgivet i:J Infect Dis
Main Authors: Thaden, Joshua T., Keller, Ashley E., Shire, Norah J., Camara, M. Margarita, Otterson, Linda, Huband, Mike, Guenther, Caitlin M., Zhao, Wei, Warrener, Paul, Stover, C. Kendall, Fowler, Vance G., DiGiandomenico, Antonio
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Major Articles and Brief Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721907/
https://ncbi.nlm.nih.gov/pubmed/26333940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv436
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