A Novel Anti-PcrV Antibody Providing Enhanced Protection against Pseudomonas aeruginosa in Multiple Animal Infection Models

Pseudomonas aeruginosa is a major cause of hospital-acquired infections, particularly in mechanically ventilated patients, and it is the leading cause of death in cystic fibrosis patients. A key virulence factor associated with disease severity is the P. aeruginosa type III secretion system (T3SS),...

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Autors principals: Warrener, Paul, Varkey, Reena, Bonnell, Jessica C., DiGiandomenico, Antonio, Camara, Maria, Cook, Kimberly, Peng, Li, Zha, Jingying, Chowdury, Partha, Sellman, Bret, Stover, C. Kendall
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136058/
https://ncbi.nlm.nih.gov/pubmed/24841258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02643-14
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