Pseudomonas aeruginosa Bacteremic Patients Exhibit Nonprotective Antibody Titers Against Therapeutic Antibody Targets PcrV and Psl Exopolysaccharide

Background. The type 3 secretion protein PcrV and Psl exopolysaccharide are promising therapeutic antibody targets against Pseudomonas aeruginosa. We examined P. aeruginosa bloodstream infection (BSI) isolates for the ability to express PcrV and Psl and evaluated corresponding patient serum for acti...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Thaden, Joshua T., Keller, Ashley E., Shire, Norah J., Camara, M. Margarita, Otterson, Linda, Huband, Mike, Guenther, Caitlin M., Zhao, Wei, Warrener, Paul, Stover, C. Kendall, Fowler, Vance G., DiGiandomenico, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721907/
https://ncbi.nlm.nih.gov/pubmed/26333940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv436
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