Identification of broadly protective human antibodies to Pseudomonas aeruginosa exopolysaccharide Psl by phenotypic screening

Pseudomonas aeruginosa is a leading cause of hospital-associated infections in the seriously ill, and the primary agent of chronic lung infections in cystic fibrosis patients. A major obstacle to effective control of P. aeruginosa infections is its intrinsic resistance to most antibiotic classes, wh...

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Main Authors: DiGiandomenico, Antonio, Warrener, Paul, Hamilton, Melissa, Guillard, Sandrine, Ravn, Peter, Minter, Ralph, Camara, Maria Margarita, Venkatraman, Vignesh, MacGill, Randall S., Lin, Jia, Wang, Qun, Keller, Ashley Elaine, Bonnell, Jessica C., Tomich, Mladen, Jermutus, Lutz, McCarthy, Michael P., Melnick, David A., Suzich, JoAnn A., Stover, C. Kendall
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405507/
https://ncbi.nlm.nih.gov/pubmed/22734046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120033
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