Identification of broadly protective human antibodies to Pseudomonas aeruginosa exopolysaccharide Psl by phenotypic screening

Pseudomonas aeruginosa is a leading cause of hospital-associated infections in the seriously ill, and the primary agent of chronic lung infections in cystic fibrosis patients. A major obstacle to effective control of P. aeruginosa infections is its intrinsic resistance to most antibiotic classes, wh...

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Hlavní autoři: DiGiandomenico, Antonio, Warrener, Paul, Hamilton, Melissa, Guillard, Sandrine, Ravn, Peter, Minter, Ralph, Camara, Maria Margarita, Venkatraman, Vignesh, MacGill, Randall S., Lin, Jia, Wang, Qun, Keller, Ashley Elaine, Bonnell, Jessica C., Tomich, Mladen, Jermutus, Lutz, McCarthy, Michael P., Melnick, David A., Suzich, JoAnn A., Stover, C. Kendall
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405507/
https://ncbi.nlm.nih.gov/pubmed/22734046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120033
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