Response to RAG-Mediated V(D)J Cleavage by NBS1 and γ-H2AX

Genetic disorders affecting cellular responses to DNA damage are characterized by high rates of translocations involving antigen receptor loci and increased susceptibility to lymphoid malignancies. We report that the Nijmegen breakage syndrome protein (NBS1) and histone γ-H2AX, which associate with...

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Publicado no:Science
Main Authors: Chen, Hua Tang, Bhandoola, Avinash, Difilippantonio, Michael J., Zhu, Jie, Brown, Martin J., Tai, Xuguang, Rogakou, Emmy P., Brotz, Tilmann M., Bonner, William M., Ried, Thomas, Nussenzweig, André
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721589/
https://ncbi.nlm.nih.gov/pubmed/11110662
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