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Response to RAG-Mediated V(D)J Cleavage by NBS1 and γ-H2AX
Genetic disorders affecting cellular responses to DNA damage are characterized by high rates of translocations involving antigen receptor loci and increased susceptibility to lymphoid malignancies. We report that the Nijmegen breakage syndrome protein (NBS1) and histone γ-H2AX, which associate with...
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| 發表在: | Science |
|---|---|
| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2000
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4721589/ https://ncbi.nlm.nih.gov/pubmed/11110662 |
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