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Conformational heterogeneity of the Roc domains in C. tepidum Roc–COR and implications for human LRRK2 Parkinson mutations

Ras of complex proteins (Roc) is a Ras-like GTP-binding domain that always occurs in tandem with the C-terminal of Roc (COR) domain and is found in bacteria, plants and animals. Recently, it has been shown that Roco proteins belong to the family of G-proteins activated by nucleotide (nt)-dependent d...

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Detalles Bibliográficos
Publicado en:Biosci Rep
Main Authors: Rudi, Katharina, Ho, Franz Y., Gilsbach, Bernd K., Pots, Henderikus, Wittinghofer, Alfred, Kortholt, Arjan, Klare, Johann P.
Formato: Artigo
Idioma:Inglês
Publicado: Portland Press Ltd. 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721548/
https://ncbi.nlm.nih.gov/pubmed/26310572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20150128
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