Structure of the Roc–COR domain tandem of C. tepidum, a prokaryotic homologue of the human LRRK2 Parkinson kinase

Ras of complex proteins (Roc) belongs to the superfamily of Ras-related small G-proteins that always occurs in tandem with the C-terminal of Roc (COR) domain. This Roc–COR tandem is found in the bacterial and eukaryotic world. Its most prominent member is the leucine-rich repeat kinase LRRK2, which...

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Bibliografiska uppgifter
Huvudupphovsmän: Gotthardt, Katja, Weyand, Michael, Kortholt, Arjan, Van Haastert, Peter J M, Wittinghofer, Alfred
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519104/
https://ncbi.nlm.nih.gov/pubmed/18650931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.150
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