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Oscillatory stress stimulation uncovers an Achilles heel of the yeast MAPK signaling network

Cells must interpret environmental information that often changes over time. We systematically monitored growth of yeast cells under various frequencies of oscillating osmotic stress. Growth was severely inhibited at a particular resonance frequency, at which cells show hyperactivated transcriptiona...

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Publicado en:Science
Main Authors: Mitchell, Amir, Wei, Ping, Lim, Wendell A.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721531/
https://ncbi.nlm.nih.gov/pubmed/26586187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab0892
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