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The RhoJ-BAD signaling network: An Achilles’ heel for BRAF mutant melanomas
Genes and pathways that allow cells to cope with oncogene-induced stress represent selective cancer therapeutic targets that remain largely undiscovered. In this study, we identify a RhoJ signaling pathway that is a selective therapeutic target for BRAF mutant cells. RhoJ deletion in BRAF mutant mel...
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Publicado no: | PLoS Genet |
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Principais autores: | , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5549996/ https://ncbi.nlm.nih.gov/pubmed/28753606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006913 |
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