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Oscillatory stress stimulation uncovers an Achilles heel of the yeast MAPK signaling network

Cells must interpret environmental information that often changes over time. We systematically monitored growth of yeast cells under various frequencies of oscillating osmotic stress. Growth was severely inhibited at a particular resonance frequency, at which cells show hyperactivated transcriptiona...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Mitchell, Amir, Wei, Ping, Lim, Wendell A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721531/
https://ncbi.nlm.nih.gov/pubmed/26586187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab0892
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