Alemtuzumab in T-cell large granular lymphocytic leukaemia: a phase 2 study

BACKGROUND: T-cell large granular lymphocytic leukemia (T-LGL) is a lymphoproliferative disease presenting with immune-mediated cytopenias and characterized by clonal expansion of cytotoxic CD3(+)CD8(+) lymphocytes. Methotrexate, cyclosporine, or cyclophosphamide improve cytopenias in 50% of patient...

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Publicat a:Lancet Haematol
Autors principals: Dumitriu, Bogdan, Ito, Sawa, Feng, Xingmin, Stephens, Nicole, Yunce, Muharrem, Kajigaya, Sachiko, Melenhorst, Joseph J., Rios, Olga, Scheinberg, Priscila, Chinian, Fariba, Keyvanfar, Keyvan, Battiwalla, Minoo, Wu, Colin O., Maric, Irina, Xi, Liqiang, Raffeld, Mark, Muranski, Pawel, Townsley, Danielle M., Young, Neal S., Barrett, Austin John, Scheinberg, Phillip
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721315/
https://ncbi.nlm.nih.gov/pubmed/26765645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2352-3026(15)00227-6
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