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Alemtuzumab in T-cell large granular lymphocytic leukaemia: a phase 2 study

BACKGROUND: T-cell large granular lymphocytic leukemia (T-LGL) is a lymphoproliferative disease presenting with immune-mediated cytopenias and characterized by clonal expansion of cytotoxic CD3(+)CD8(+) lymphocytes. Methotrexate, cyclosporine, or cyclophosphamide improve cytopenias in 50% of patient...

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Detalhes bibliográficos
Publicado no:Lancet Haematol
Main Authors: Dumitriu, Bogdan, Ito, Sawa, Feng, Xingmin, Stephens, Nicole, Yunce, Muharrem, Kajigaya, Sachiko, Melenhorst, Joseph J., Rios, Olga, Scheinberg, Priscila, Chinian, Fariba, Keyvanfar, Keyvan, Battiwalla, Minoo, Wu, Colin O., Maric, Irina, Xi, Liqiang, Raffeld, Mark, Muranski, Pawel, Townsley, Danielle M., Young, Neal S., Barrett, Austin John, Scheinberg, Phillip
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721315/
https://ncbi.nlm.nih.gov/pubmed/26765645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2352-3026(15)00227-6
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