Alemtuzumab in T-cell large granular lymphocytic leukaemia: a phase 2 study

BACKGROUND: T-cell large granular lymphocytic leukemia (T-LGL) is a lymphoproliferative disease presenting with immune-mediated cytopenias and characterized by clonal expansion of cytotoxic CD3(+)CD8(+) lymphocytes. Methotrexate, cyclosporine, or cyclophosphamide improve cytopenias in 50% of patient...

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Enregistré dans:
Détails bibliographiques
Publié dans:Lancet Haematol
Auteurs principaux: Dumitriu, Bogdan, Ito, Sawa, Feng, Xingmin, Stephens, Nicole, Yunce, Muharrem, Kajigaya, Sachiko, Melenhorst, Joseph J., Rios, Olga, Scheinberg, Priscila, Chinian, Fariba, Keyvanfar, Keyvan, Battiwalla, Minoo, Wu, Colin O., Maric, Irina, Xi, Liqiang, Raffeld, Mark, Muranski, Pawel, Townsley, Danielle M., Young, Neal S., Barrett, Austin John, Scheinberg, Phillip
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721315/
https://ncbi.nlm.nih.gov/pubmed/26765645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2352-3026(15)00227-6
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