Epigenetic landscape of the TERT promoter: a potential biomarker for high risk AML/MDS

Although recent observations implicate the importance of telomerase activity in acute myeloid leukaemia (AML), the roles of epigenetic regulations of the TERT gene in leukaemogenesis, drug resistance and clinical prognosis in AML are not fully understood. We developed a quantitative pyrosequencing-b...

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Pubblicato in:Br J Haematol
Autori principali: Zhao, Xin, Tian, Xin, Kajigaya, Sachiko, Cantilena, Caroline R., Strickland, Stephen, Savani, Bipin N., Mohan, Sanjay, Feng, Xingmin, Keyvanfar, Keyvan, Dunavin, Neil, Townsley, Danielle M., Dumitriu, Bogdan, Battiwalla, Minoo, Rezvani, Katayoun, Young, Neal S., Barrett, A. John, Ito, Sawa
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5245983/
https://ncbi.nlm.nih.gov/pubmed/27433923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.14244
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