Epigenetic landscape of the TERT promoter: a potential biomarker for high risk AML/MDS

Although recent observations implicate the importance of telomerase activity in acute myeloid leukaemia (AML), the roles of epigenetic regulations of the TERT gene in leukaemogenesis, drug resistance and clinical prognosis in AML are not fully understood. We developed a quantitative pyrosequencing-b...

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Detalhes bibliográficos
Publicado no:Br J Haematol
Main Authors: Zhao, Xin, Tian, Xin, Kajigaya, Sachiko, Cantilena, Caroline R., Strickland, Stephen, Savani, Bipin N., Mohan, Sanjay, Feng, Xingmin, Keyvanfar, Keyvan, Dunavin, Neil, Townsley, Danielle M., Dumitriu, Bogdan, Battiwalla, Minoo, Rezvani, Katayoun, Young, Neal S., Barrett, A. John, Ito, Sawa
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5245983/
https://ncbi.nlm.nih.gov/pubmed/27433923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.14244
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