Renal cell carcinomas of chronic kidney disease patients harbor the mutational signature of carcinogenic aristolochic acid

Aristolochic acid (AA) is a potent dietary cytotoxin and carcinogen, and an established etiological agent underlying severe human nephropathies and associated upper urinary tract urothelial cancers, collectively designated aristolochic acid nephropathy (AAN). Its genome-wide mutational signature, ma...

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Bibliographic Details
Published in:Int J Cancer
Main Authors: Jelaković, Bojan, Castells, Xavier, Tomić, Karla, Ardin, Maude, Karanović, Sandra, Zavadil, Jiri
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720973/
https://ncbi.nlm.nih.gov/pubmed/25403517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29338
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