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Renal cell carcinomas of chronic kidney disease patients harbor the mutational signature of carcinogenic aristolochic acid
Aristolochic acid (AA) is a potent dietary cytotoxin and carcinogen, and an established etiological agent underlying severe human nephropathies and associated upper urinary tract urothelial cancers, collectively designated aristolochic acid nephropathy (AAN). Its genome-wide mutational signature, ma...
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| Publié dans: | Int J Cancer |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4720973/ https://ncbi.nlm.nih.gov/pubmed/25403517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29338 |
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