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Formalin-fixed paraffin-embedded tissue as a source for quantitation of carcinogen DNA adducts: aristolochic acid as a prototype carcinogen

DNA adducts are a measure of internal exposure to genotoxicants. However, the measurement of DNA adducts in molecular epidemiology studies often is precluded by the lack of fresh tissue. In contrast, formalin-fixed paraffin-embedded (FFPE) tissues frequently are accessible, although technical challe...

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Bibliografski detalji
Glavni autori: Yun, Byeong Hwa, Yao, Lihua, Jelaković, Bojan, Nikolić, Jovan, Dickman, Kathleen G., Grollman, Arthur P., Rosenquist, Thomas A., Turesky, Robert J.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146416/
https://ncbi.nlm.nih.gov/pubmed/24776219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu101
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