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Multi-Class Carcinogenic DNA Adduct Quantification in Formalin-Fixed Paraffin-Embedded Tissues by Ultra-Performance Liquid Chromatography–Tandem Mass Spectrometry

DNA adducts are a measure of internal exposure to genotoxicants and an important biomarker for human risk assessment. However, the employment of DNA adducts as biomarkers in human studies is often restricted because fresh frozen tissues are not available. In contrast, formalin-fixed paraffin embedde...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Guo, Jingshu, Yun, Byeong Hwa, Upadhyaya, Pramod, Yao, Lihua, Krishnamachari, Sesha, Rosenquist, Thomas A., Grollman, Arthur P., Turesky, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854775/
https://ncbi.nlm.nih.gov/pubmed/27043225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b00124
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