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Multi-Class Carcinogenic DNA Adduct Quantification in Formalin-Fixed Paraffin-Embedded Tissues by Ultra-Performance Liquid Chromatography–Tandem Mass Spectrometry

DNA adducts are a measure of internal exposure to genotoxicants and an important biomarker for human risk assessment. However, the employment of DNA adducts as biomarkers in human studies is often restricted because fresh frozen tissues are not available. In contrast, formalin-fixed paraffin embedde...

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Библиографические подробности
Опубликовано в: :Anal Chem
Главные авторы: Guo, Jingshu, Yun, Byeong Hwa, Upadhyaya, Pramod, Yao, Lihua, Krishnamachari, Sesha, Rosenquist, Thomas A., Grollman, Arthur P., Turesky, Robert J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854775/
https://ncbi.nlm.nih.gov/pubmed/27043225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b00124
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