A Rapid Throughput Method to Extract DNA from Formalin-Fixed Paraffin-Embedded Tissues for Biomonitoring Carcinogenic DNA Adducts

Formalin-fixed paraffin-embedded (FFPE) tissues are rarely used for screening DNA adducts of carcinogens because the harsh conditions required to reverse the formaldehyde-mediated DNA cross-links can destroy DNA adducts. We recently adapted a commercial silica-based column kit used in genomics to ma...

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Detaylı Bibliyografya
Yayımlandı:Chem Res Toxicol
Asıl Yazarlar: Yun, Byeong Hwa, Xiao, Shun, Yao, Lihua, Krishnamachari, Sesha, Rosenquist, Thomas A., Dickman, Kathleen G., Grollman, Arthur P., Murugan, Paari, Weight, Christopher J., Turesky, Robert J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5822421/
https://ncbi.nlm.nih.gov/pubmed/29120619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.7b00218
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