Aristolactam-DNA Adducts in the Renal Cortex: Biomarker of Environmental Exposure to Aristolochic Acid

Balkan endemic nephropathy is a chronic tubulointerstitial disease frequently accompanied by urothelial cell carcinomas of the upper urinary tract. This disorder has recently been linked to exposure to aristolochic acid, a powerful nephrotoxin and human carcinogen. Following metabolic activation, ar...

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Detalhes bibliográficos
Main Authors: Jelaković, Bojan, Karanović, Sandra, Vuković-Lela, Ivana, Miller, Frederick, Edwards, Karen, Nikolić, Jovan, Tomić, Karla, Slade, Neda, Brdar, Branko, Turesky, Robert, Stipanćić, Želimir, Dittrich, Damir, Grollman, Arthur P., Dickman, Kathleen G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560912/
https://ncbi.nlm.nih.gov/pubmed/22071594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2011.371
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