Neuronal Glutathione Content and Antioxidant Capacity can be Normalized In Situ by N-acetyl Cysteine Concentrations Attained in Human Cerebrospinal Fluid

N-acetyl cysteine (NAC) supports the synthesis of glutathione (GSH), an essential substrate for fast, enzymatically catalyzed oxidant scavenging and protein repair processes. NAC is entering clinical trials for adrenoleukodystrophy, Parkinson’s disease, schizophrenia, and other disorders in which ox...

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Detalhes bibliográficos
Publicado no:Neurotherapeutics
Main Authors: Reyes, Reno C., Cittolin-Santos, Giordano Fabricio, Kim, Ji-Eun, Won, Seok Joon, Brennan-Minnella, Angela M., Katz, Maya, Glass, Graham A., Swanson, Raymond A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720670/
https://ncbi.nlm.nih.gov/pubmed/26572666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-015-0404-4
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