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Neuronal Glutathione Content and Antioxidant Capacity can be Normalized In Situ by N-acetyl Cysteine Concentrations Attained in Human Cerebrospinal Fluid

N-acetyl cysteine (NAC) supports the synthesis of glutathione (GSH), an essential substrate for fast, enzymatically catalyzed oxidant scavenging and protein repair processes. NAC is entering clinical trials for adrenoleukodystrophy, Parkinson’s disease, schizophrenia, and other disorders in which ox...

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Dettagli Bibliografici
Pubblicato in:Neurotherapeutics
Autori principali: Reyes, Reno C., Cittolin-Santos, Giordano Fabricio, Kim, Ji-Eun, Won, Seok Joon, Brennan-Minnella, Angela M., Katz, Maya, Glass, Graham A., Swanson, Raymond A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720670/
https://ncbi.nlm.nih.gov/pubmed/26572666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-015-0404-4
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