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Suppression of transcriptional drift extends C. elegans lifespan by postponing the onset of mortality

Longevity mechanisms increase lifespan by counteracting the effects of aging. However, whether longevity mechanisms counteract the effects of aging continually throughout life, or whether they act during specific periods of life, preventing changes that precede mortality is unclear. Here, we uncover...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Rangaraju, Sunitha, Solis, Gregory M, Thompson, Ryan C, Gomez-Amaro, Rafael L, Kurian, Leo, Encalada, Sandra E, Niculescu, Alexander B, Salomon, Daniel R, Petrascheck, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720515/
https://ncbi.nlm.nih.gov/pubmed/26623667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08833
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