Suppression of transcriptional drift extends C. elegans lifespan by postponing the onset of mortality

Longevity mechanisms increase lifespan by counteracting the effects of aging. However, whether longevity mechanisms counteract the effects of aging continually throughout life, or whether they act during specific periods of life, preventing changes that precede mortality is unclear. Here, we uncover...

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Udgivet i:eLife
Main Authors: Rangaraju, Sunitha, Solis, Gregory M, Thompson, Ryan C, Gomez-Amaro, Rafael L, Kurian, Leo, Encalada, Sandra E, Niculescu, Alexander B, Salomon, Daniel R, Petrascheck, Michael
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2015
Fag:
Computational and Systems Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720515/
https://ncbi.nlm.nih.gov/pubmed/26623667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08833
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